Naringenin, Catalog: 1772

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5,7,4'-Trihydroxyflavanone; 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; NGEN

PRODUCT SUMMARY

Alternate Names 5,7,4'-Trihydroxyflavanone; 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; NGEN

Appearance Brown solid

CAS # 480-41-1

Molecular Formula C₁₅H₁₂O₅

Molecular Weight 272.26

Purity ≥98% by TLC

Solubility DMSO or EtOH (50 mg/ml)

SMILES C1C(OC2=CC(=CC(=C2C1=O)O)O)C3=CC=C(C=C3)O

InChi InChI=1S/C15H12O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-6,13,16-18H,7H2

InChi Key FTVWIRXFELQLPI-UHFFFAOYSA-N

PubChem CID 932

MDL Number MFCD00006844

Storage Conditions -20°C

Shipping Conditions Gel Pack

Usage For Research Use Only! Not For Use in Humans.

Handling Do not take it internally. Wear a glove and mask when handling the product. Protect from air and moisture.

DESCRIPTION

Naringenin is a flavonoid compound found in various fruits, particularly in citrus fruits like oranges, grapefruits, and lemons. It acts as an antioxidant, free radical scavenger, and carbohydrate metabolism promoter. It shows cytotoxicity in various human cell lines and promotes apoptosis in rat C6 glioma model. Naringenin seems to protect LDL-receptor deficient mice from the obesity effects of a high-fat diet. Also lowers the plasma and hepatic cholesterol concentrations by suppressing HMG-CoA reductase