Madrasin, Catalog: B1278
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2-((7-Methoxy-4-methylquinazolin-2-yl)amino)-5,6-dimethylpyrimidin-4(3H)-one
2-((7-Methoxy-4-methylquinazolin-2-yl)amino)-5,6-dimethylpyrimidin-4(3H)-one
Alternate Names 2-((7-Methoxy-4-methylquinazolin-2-yl)amino)-5,6-dimethylpyrimidin-4(3H)-one
Appearance White to off-white solid
CAS # 374913-63-0
Molecular Formula C₁₆H₁₇N₅O₂
Molecular Weight 311.34
Purity ≥ 97% by HPLC
Solubility DMSO (~ 1 mg/ml)
SMILES CC1=C(NC(=NC1=O)NC2=NC3=C(C=CC(=C3)OC)C(=N2)C)C
InChi InChI=1S/C16H17N5O2/c1-8-9(2)17-16(20-14(8)22)21-15-18-10(3)12-6-5-11(23-4)7-13(12)19-15/h5-7H,1-4H3,(H2,17,18,19,20,21,22)
InChi Key QQJIYKXTEMDJFM-UHFFFAOYSA-N
PubChem CID 816255
MDL Number MFCD02233199
Storage Conditions -20°C
Shipping Conditions Gel Pack
Usage For Research Use Only! Not For Use in Humans.
Handling Do not take it internally. Wear a glove and mask when handling the product. Protect from air and moisture.
Madrasin is a potent and cell-permeable pre-mRNA splicing inhibitor. It interferes with the early stages of spliceosome assembly. Madrasin