Madrasin, Catalog: B1278

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 2-((7-Methoxy-4-methylquinazolin-2-yl)amino)-5,6-dimethylpyrimidin-4(3H)-one

PRODUCT SUMMARY

Alternate Names  2-((7-Methoxy-4-methylquinazolin-2-yl)amino)-5,6-dimethylpyrimidin-4(3H)-one

Appearance White to off-white solid

CAS # 374913-63-0 

Molecular Formula C₁₆H₁₇N₅O₂

Molecular Weight 311.34

Purity ≥ 97% by HPLC

Solubility DMSO (~ 1 mg/ml)

SMILES CC1=C(NC(=NC1=O)NC2=NC3=C(C=CC(=C3)OC)C(=N2)C)C

InChi InChI=1S/C16H17N5O2/c1-8-9(2)17-16(20-14(8)22)21-15-18-10(3)12-6-5-11(23-4)7-13(12)19-15/h5-7H,1-4H3,(H2,17,18,19,20,21,22)

InChi Key QQJIYKXTEMDJFM-UHFFFAOYSA-N

PubChem CID 816255

MDL Number MFCD02233199

Storage Conditions -20°C

Shipping Conditions Gel Pack

Usage For Research Use Only! Not For Use in Humans.

Handling Do not take it internally. Wear a glove and mask when handling the product. Protect from air and moisture.

 

DESCRIPTION

Madrasin is a potent and cell-permeable pre-mRNA splicing inhibitor. It interferes with the early stages of spliceosome assembly. Madrasin