Isoliquiritigenin, Catalog: 2528

Alternate Names 1-(2E,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one; GU 17; ISL

Appearance Yellow to orange solid

CAS # 961-29-5

Molecular Formula C₁₅H₁₂O₄

Molecular Weight 256.26

Purity ≥ 95% by HPLC

Solubility DMSO (20 mg/ml)

SMILES C1=CC(=CC=C1C=CC(=O)C2=C(C=C(C=C2)O)O)O

InChi InChI=1S/C15H12O4/c16-11-4-1-10(2-5-11)3-8-14(18)13-7-6-12(17)9-15(13)19/h1-9,16-17,19H/b8-3+

InChi Key DXDRHHKMWQZJHT-FPYGCLRLSA-N

PubChem CID 638278

MDL Number MFCD00075907

Storage Conditions -20°C

Shipping Conditions Gel Pack

Usage For Research Use Only! Not For Use in Humans.

Handling Do not take it internally. Wear a glove and mask when handling the product. Protect from air and moisture.

Isoliquiritigenin (ISL) is a flavonoid found in licorice root and several other plants. Displays antioxidant, anti-inflammatory, and antitumor activities as well as hepatoprotection against steatosis-induced oxidative stress. Acts as a soluble guanylyl cyclase activator. Also displays chemoprevention by induction of phase 2 enzymes such as quinone reductase, that protect cells against reactive, toxic, and potentially carcinogenic species.