VK3-OCH3, Catalog: 2694
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2-[(2-Methoxyethyl)thio]-3-methyl-1,4-naphthalenedione; VK3-OMe
2-[(2-Methoxyethyl)thio]-3-methyl-1,4-naphthalenedione; VK3-OMe
Alternate Names 2-[(2-Methoxyethyl)thio]-3-methyl-1,4-naphthalenedione; VK3-OMe
Appearance Light orange to dark orange solid
CAS # 255906-59-3
Molecular Formula C₁₄H₁₄O₃S
Molecular Weight 262.32
Purity ≥ 98% by HPLC
Solubility DMSO (~10 mg/ml)
SMILES CC1=C(C(=O)C2=CC=CC=C2C1=O)SCCOC
InChi InChI=1S/C14H14O3S/c1-9-12(15)10-5-3-4-6-11(10)13(16)14(9)18-8-7-17-2/h3-6H,7-8H2,1-2H3
InChi Key JTCRCMIBIBLUOK-UHFFFAOYSA-N
PubChem CID 9903359
MDL Number MFCD22575003
Storage Conditions -20°C
Shipping Conditions Gel Pack
Usage For Research Use Only! Not For Use in Humans.
Handling Do not take it internally. Wear a glove and mask when handling the product. Protect from air and moisture.
VK3-OCH3 is a Vitamin K3 (Menadione) analog that displays potent antitumor activity. It has been shown to induce G2/M arrest and apoptosis in neuroblastoma cells with much less cytotoxicity towards normal cells. VK3-OCH3 is believed to act through up-regulation of heme oxygenase (HO)-1.