DDP-38003 dihydrochloride, Catalog: B1958

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N-[4-[(1R,2S)-2-aminocyclopropyl]cyclohexyl]-4-(4-methylpiperazin-1-yl)benzamide;dihydrochloride

PRODUCT SUMMARY

Alternate Names N-[4-[(1R,2S)-2-aminocyclopropyl]cyclohexyl]-4-(4-methylpiperazin-1-yl)benzamide;dihydrochloride

Appearance Crystalline solid

CAS # 1831167-98-6

Molecular Formula C₂₁H₂₈Cl₂N₄O

Molecular Weight 423.38

Purity ≥ 98% by HPLC

Solubility DMSO

SMILES CN1CCN(CC1)C2=CC=C(C=C2)C(=O)NC3CCC(CC3)C4CC4N.Cl.Cl

InChi InChI=1S/C21H32N4O.2ClH/c1-24-10-12-25(13-11-24)18-8-4-16(5-9-18)21(26)23-17-6-2-15(3-7-17)19-14-20(19)22;;/h4-5,8-9,15,17,19-20H,2-3,6-7,10-14,22H2,1H3,(H,23,26);2*1H/t15?,17?,19-,20+;;/m1../s1

InChi Key HFUZPOURCSSHLY-OAXVCWOXSA-N

PubChem CID 129627552

Storage Conditions -20°C

Shipping Conditions Gel Pack

Usage For Research Use Only! Not For Use in Humans.

Handling Do not take it internally. Wear a glove and mask when handling the product. Protect from air and moisture.

DESCRIPTION

DDP-38003 dihydrochloride is a potent, orally available inhibitor of histone lysine-specific demethylase 1A (KDM1A/LSD1) with an IC₅₀ of 84 nM.