3-Deazaadenosine, Catalog: 2771

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1-β-D-ribofuranosyl-1H-Imidazo[4,5-c]pyridin-4-amine; 3-DZA; deaza-Ado; c3Ado

PRODUCT SUMMARY

Alternate Names 1-β-D-ribofuranosyl-1H-Imidazo[4,5-c]pyridin-4-amine; 3-DZA; deaza-Ado; c3Ado

Appearance White to off-white solid

CAS # 6736-58-9

Molecular Formula C₁₁H₁₄N₄O₄

Molecular Weight 266.25

Purity ≥ 98%

Solubility H₂O (~10 mg/ml)

SMILES C1=CN=C(C2=C1N(C=N2)C3C(C(C(O3)CO)O)O)N

InChi InChI=1S/C11H14N4O4/c12-10-7-5(1-2-13-10)15(4-14-7)11-9(18)8(17)6(3-16)19-11/h1-2,4,6,8-9,11,16-18H,3H2,(H2,12,13)/t6-,8-,9-,11-/m1/s1

InChi Key DBZQFUNLCALWDY-PNHWDRBUSA-N

PubChem CID 23190

MDL Number MFCD00153951

Storage Conditions -20°C

Shipping Conditions Gel Pack

Usage For Research Use Only! Not For Use in Humans.

Handling Do not take it internally. Wear a glove and mask when handling the product. Protect from air and moisture.

DESCRIPTION

3-Deazaadenosine (3-DZA) is an inhibitor of SAH (S-adenosylhomocysteine) hydrolase (Ki = 3.9 μM). It has anti-inflammatory properties, inhibiting leukocyte adhesion and chemotaxis, lymphocyte-mediated cytolysis, phagocytosis, degranulation, and NF-κB signaling. 3-DZA also has anti-viral and anti-bacterial activities.