Takinib, Catalog: B2324
IN STOCK!
US$0.00
3-N-(1-Propylbenzimidazol-2-yl)benzene-1,3-dicarboxamide
3-N-(1-Propylbenzimidazol-2-yl)benzene-1,3-dicarboxamide
Alternate Names 3-N-(1-Propylbenzimidazol-2-yl)benzene-1,3-dicarboxamide
Appearance Crystalline solid
CAS # 1111556-37-6
Molecular Formula C₁₈H₁₈N₄O₂
Molecular Weight 322.36
Purity ≥ 98% by HPLC
Solubility >25 mg/ml in DMSO
SMILES CCCN1C2=CC=CC=C2N=C1NC(=O)C3=CC=CC(=C3)C(=O)N
InChi InChI=1S/C18H18N4O2/c1-2-10-22-15-9-4-3-8-14(15)20-18(22)21-17(24)13-7-5-6-12(11-13)16(19)23/h3-9,11H,2,10H2,1H3,(H2,19,23)(H,20,21,24)
InChi Key UOZVVPXKJGOFIG-UHFFFAOYSA-N
PubChem CID 37750349
Storage Conditions -20°C
Shipping Conditions Gel Pack
Usage For Research Use Only! Not For Use in Humans.
Handling Do not take it internally. Wear a glove and mask when handling the product. Protect from air and moisture.
Takinib is a potent and selective TAK1 inhibitor (IC₅₀ = 9.5 nM). Sensitizes cells to TNF-α-induced cell death, with potential implications for cancer and autoimmune diseases.