Caspase-3 inhibitor, Z-DQMD-FMK, Catalog: 2782

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Z-DQMD-FMK,Benzyloxycarbonyl-Asp(OMe)-Gln-Met-Asp(OMe)-fluoromethylketone

PRODUCT SUMMARY

Alternate Names Z-DQMD-FMK,Benzyloxycarbonyl-Asp(OMe)-Gln-Met-​Asp(OMe)-fluoromethylketone

Peptide Sequence Z-Asp(OMe)-Gln-Met-Asp(OMe)-FMK

Appearance Lyophilzed solid

Molecular Formula C₂₉H₄₀FN₅O₁₁S

Molecular Weight 685.72

Purity ≥ 85% by HPLC

Solubility DMSO (~ 200 mg/ml)

SMILES O=C(OC)C[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(OCC1=CC=CC=C1)=O)CC(OC)=O)=O)CCC(N)=O)=O)CCSC)=O)C(CF)=O

InChi InChI=1S/C29H40FN5O11S/c1-44-24(38)13-20(22(36)15-30)34-27(41)19(11-12-47-3)33-26(40)18(9-10-23(31)37)32-28(42)21(14-25(39)45-2)35-29(43)46-16-17-7-5-4-6-8-17/h4-8,18-21H,9-16H2,1-3H3,(H2,31,37)(H,32,42)(H,33,40)(H,34,41)(H,35,43)/t18-,19-,20-,21-/m0/s1

InChi Key QFITYVNVMNJELE-TUFLPTIASA-N

Storage Conditions -20°C

Shipping Conditions Gel Pack

Usage For Research Use Only! Not For Use in Humans.

Handling Do not take it internally. Wear a glove and mask when handling the product. Protect from air and moisture.

DESCRIPTION

Z-DQMD-FMK is a cell-permeable caspase-3 inhibitor. Inhibits MG-132-induced small cell lung cancer cell death in vitro.