Destruxin A, Catalog: B2947 (Copy)

Alternate Names 3-(butan-2-yl)-5,8,9-trimethyl-6-(propan-2-yl)-16-(prop-2-en-1-yl)dodecahydropyrrolo[1,2-d][1,4,7,10,13,16]oxapentaazacyclononadecine-1,4,7,10,14,17(11h,16h)-hexone; (3S,6S,9S,16R,21aS)-16-Allyl-3-[(2S)-2-butanyl]-6-isopropyl-5,8,9-trimethyldodecahydropyrrolo[1,2-d][1,4,7,10,13,16]oxapentaazacyclononadecine-1,4,7,10,14,17(11H,16H)-hexone; NSC361126.

Appearance Solid

CAS # 6686-70-0

Molecular Formula C₂₉H₄₇N₅O₇

Molecular Weight 577.71

Purity ≥ 96%

Solubility 10 mg/ml in DMSO

SMILES CCC(C)C1C(=O)N(C(C(=O)N(C(C(=O)NCCC(=O)OC(C(=O)N2CCCC2C(=O)N1)CC=C)C)C)C(C)C)C   

InChi InChI=1S/C29H47N5O7/c1-9-12-21-27(38)34-16-11-13-20(34)26(37)31-23(18(5)10-2)28(39)33(8)24(17(3)4)29(40)32(7)19(6)25(36)30-15-14-22(35)41-21/h9,17-21,23-24H,1,10-16H2,2-8H3,(H,30,36)(H,31,37)

InChi Key XIYSEKITPHTMJT-UHFFFAOYSA-N

PubChem CID 122810

Storage Condiions -20ºC

Shipping Conditions Gel Pack

Usage For Research Use Only! Not For Use in Humans.

Handling Do not take it internally. Wear gloves and a mask when handling the product! Avoid contact by all modes of exposure.

Destruxin A is a cyclic hexadepsipeptide metabolite from the fungus Metarhizium anisopliae. It is produced by certain species of entomopathogenic fungi, including Metarhizium anisopliae and Beauveria bassiana. Destruxin A exhibits insecticidal properties and is used in agricultural and biological control applications. Destruxin A acts as a biopesticide and exerts its insecticidal effects by targeting the immune system and disrupting cellular processes in insects. It interacts with the insect midgut epithelial cells, causing cell damage, disruption of cell membranes, and alteration of ion transport, leading to insect death. Destruxin A and other destruxin compounds have been the subject of ongoing research to explore their potential applications in pest control and agriculture.