Firocoxib, Catalog: B1986
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3-(Cyclopropylmethoxy)-4-(4-methylsulfonylphenyl)-5,5-dimethylfuranone; ML1785713
3-(Cyclopropylmethoxy)-4-(4-methylsulfonylphenyl)-5,5-dimethylfuranone; ML1785713
Alternate Names 3-(Cyclopropylmethoxy)-4-(4-methylsulfonylphenyl)-5,5-dimethylfuranone; ML1785713
Appearance Crystalline solid
CAS # 189954-96-9
Molecular Formula C₁₇H₂₀O₅S
Molecular Weight 336.4
Purity ≥98% by HPLC
Solubility DMSO
SMILES CC1(C(=C(C(=O)O1)OCC2CC2)C3=CC=C(C=C3)S(=O)(=O)C)C
InChi InChI=1S/C17H20O5S/c1-17(2)14(12-6-8-13(9-7-12)23(3,19)20)15(16(18)22-17)21-10-11-4-5-11/h6-9,11H,4-5,10H2,1-3H3
InChi Key FULAPETWGIGNMT-UHFFFAOYSA-N
PubChem CID 208910
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.
Handling Do not take it internally. Wear a glove and mask when handling the product. Protect from air and moisture.
Firocoxib is a non-steroidal anti-inflammatory drug (NSAID) that acts as a potent and selective cyclooxygenase (COX)-2 inhibitor with an IC₅₀ of 0.13 uM. Displays 58-fold selectivity for COX-2 vs COX-1. A useful veterinary drug.