Inosine Assay, Catalog: MA-0173

Catalog MA-0173

Size 100 wells

Sample Type Variety of samples including Cell & Tissue Culture Supernatants, Urine, Plasma, Serum, Other Biological Fluids, Fermentation Media, etc.

Method of Detection Fluorometric, Ex/Em = 535/587 nm

Assay Type Quantitative

Application A plate based simple, sensitive means of quantifying inosine in a variety of sample types.

Sensitivity Below ~ 100 μM

Storage Conditions -20°C

Shipping Temperature Gel Pack

Shelf Life One year from the date of delivery

Inosine, a nucleoside formed from xanthine and ribose is typically identified as an intermediate in the purine salvage pathway. Beyond that role, inosine is implicated in a number of actions: modulation of processes related to cellular respiration and ATP production; signal transduction pathways; regulation of gene expression (it is also found in tRNA) and it has been found to have immunomodulatory effects associated with purinergic signaling. Inosine has been investigated as a neuroprotective agent in Parkinson’s and Huntington’s diseases as well as a possible immunomodulatory agent in MS. Finally, inosine has been studied for its potential in treatment of spinal cord injury and in ischemic injury s a cardioprotective agent. AkrivisBio’s Inosine Assay is a simple, sensitive means of quantifying inosine in a variety of sample types with a sensitivity below ~ 100 μM.