Total Bile Acids Assay, Catalog: MA-0186

Catalog MA-0186

Size 100 wells

Sample Type Urine, Plasma, Serum, Bile, Saliva, Other Biological Fluids

Method of Detection Colorimetric, OD 405 nm 

Assay Type Quantitative

Application A plate based simple, sensitive way to measure bile acid concentration in biological samples.

Sensitivity ~1 μM

Storage Conditions -20°C

Shipping Temperature Gel Pack

Shelf Life One year from the date of delivery

Bile acids play a crucial role in the absorption of fats in the human body. They are synthesized in the liver from cholesterol and stored in the gallbladder. Upon ingestion of a meal, the gallbladder releases bile acids into the small intestine, where they emulsify dietary fats, facilitating their breakdown and subsequent absorption. This process is essential for the absorption of fat-soluble vitamins and nutrients. They also act as signaling molecules, influencing various physiological processes, including lipid and glucose metabolism. Bile acids interact with specific receptors, such as the farnesoid X receptor (FXR) and the Takeda G-protein-coupled receptor 5 (TGR5), to regulate gene expression and modulate metabolic pathways. As a result, they play a role in maintaining metabolic homeostasis and may impact conditions like obesity, diabetes, and cardiovascular disease. Elevated blood bile acids may indicate liver dysfunction, cholestasis or bile acid malabsorption. AkrivisBio’s Total Bile Acids Assay is a simple sensitive way to measure bile acid concentration in biological samples with a sensitivity of ~1 μM.