Streptokinase Activity Assay, Catalog: MA-0368

Catalog MA-0368

Size 100 wells

Sample Type Serum off the clot can be evaluated for increased plasmin activity with the addition of Streptokinase.

Method of Detection Colorimetric  405 nm

Assay Type Quantitative

Application A simple, sensitive means to evaluate the activity of Streptokinase and its effectiveness as a thrombolytic agent.

Storage Conditions -20°C

Shipping Temperature Gel Pack

Shelf Life One year from the date of delivery

Streptokinase, a protein produced by various strains of streptococci, is a therapeutic drug and is used to treat cardiovascular conditions. Streptokinase’s primary metabolic function is to convert inert plasminogen to plasmin, in a non-enzymatic process. Plasmin is very active in the breakdown of blood clots. Streptokinase binds a molecule of plasminogen, forming a complex which undergoes a conformational change, creating an active site which then acquires a proteolytic activity, converting other molecules of plasminogen to plasmin. It is used as a fibrinolytic agent to treat patients with strokes or myocardial infarction. AkrivisBio’s Streptokinase Activity Assay is a simple, sensitive means to evaluate the activity of Streptokinase and its effectiveness as a thrombolytic agent. The assay is able to detect less than 3 mU of Streptokinase activity.