Gamma Glutamyl Transferase Assay (F), Catalog: MA-0284

Catalog MA-0284

Size 100 wells

Sample Type  Cell & Tissue Lysates, Serum

Method of Detection Fluorometric, Ex/Em = 360/460 nm

Assay Type  Quantitative

Application A plate-based simple, sensitive fluorometric assay to measure to measure Gamma Glutamyl Transferase activity in a variety of samples.

Sensitivity< 1 µUnit per sample

Storage Conditions -20°C

Shipping Temperature Gel Pack

Shelf Life One year from the date of delivery

GGT plays an important role in the gamma-glutamyl cycle, essential for synthesis and degradation of glutathione. GGT enables the breakdown of extracellular glutathione, allowing cells to recycle it and maintain intracellular glutathione levels. GGT is involved in drug and xenobiotic detoxification, helping to process and eliminate potentially harmful substances through the conjugation of glutathione to a variety of chemicals, aiding in their elimination. Paradoxically, while GGT is involved in glutathione-related antioxidant processes, elevated levels of serum GGT are associated with increased oxidative stress and inflammation. This apparent contradiction is due to GGT's role in the extracellular catabolism of glutathione, leading to the production of reactive oxygen species. In general terms, GGT is used as a marker of liver function and alcohol consumption and elevated GGT levels are linked to symptoms of metabolic syndrome, including increased insulin resistance, higher triglycerides and lower HDL cholesterol and increased blood pressure. AkrivisBio’s MA-0284 Gamma Glutamyl Transferase Activity Assay is a sensitive fluorometric method of measuring GGT activity with a sensitivity below 1 µUnit per sample.